Senior Research Scientist · J-STAR Research Inc.
Lead research and development work for solid-state form studies of small-molecule drug substances, including active pharmaceutical ingredient screening and characterization workflows.
Chemist / Senior Research Scientist
Pharmaceutical solid-state chemistry, photochemistry, and fluorescent probe research.
I am a chemist with experience in small-molecule API solid-state form studies, polymorph, salt, and cocrystal screening, and BODIPY-based photochemical systems. My research background connects organic synthesis, analytical characterization, fluorescence imaging, and light-guided delivery platforms.
About
Profile
Experienced chemist working across chemicals, compounds, and pharmaceutical materials. Skilled in photochemistry-related analysis, fluorescent dyes, experimental documentation, and scientific writing, with project management experience developed through doctoral research and industry R&D.
Experience
Professional Experience
R&D Researcher · JiuRi New Materials Co., Ltd.
Prepared photoinitiator materials and optimized related technologies for new-materials research and development.
Research
Research Focus
API Solid-State Form Studies
Polymorph, salt, and cocrystal screening for small-molecule drug substances, supported by analytical characterization and structured project execution.
BODIPY Photochemistry
Developed BODIPY oxime ester photo-uncaging platforms and BODIPY-based photoacid generators for light-induced chemical and polymerization systems.
Fluorescent Probes & Imaging
Built far-red fluorescent probe systems for hypochlorous acid sensing and imaging, with experience in fluorescence microscopy and cell-culture imaging.
Interactive Process Model
A separate browser-based 3D project page visualizes wet milling, thin-film evaporation, dosing, flow-meter monitoring, vacuum condensation, and slurry collection.
Open 3D projectAPI Salt Screen Calculator
A browser-based tool for choosing acid candidates and calculating acid mass, stock concentration, and microliter dosing volume for API salt screening experiments.
Open salt screen calculatorPolymorph Screen Designer
A browser-based tool that converts approximate API solubility in common solvents into anti-solvent, evaporation, and vapor-diffusion experiments.
Open polymorph screen designerSkills
Technical Skills
Education
Education
Ph.D. in Chemistry · New Jersey Institute of Technology
Supervisor: Dr. Yuanwei Zhang. Dissertation research focused on BODIPY photo-uncaging, BODIPY photoacid generators, and far-red fluorescent probes.
M.S. in Chemistry · New Jersey Institute of Technology
B.S. in Applied Chemistry · Nanjing University
Publications
Selected Publications
- Computational and Experimental Cocrystal Screening of Tiopronin and Dapagliflozin APIs: Development and Validation of a New Virtual Screening Model. Crystal Growth & Design, 2025.
- Far-red BODIPY-based oxime esters: photo-uncaging and drug delivery. Journal of Materials Chemistry B, 2023.
- Quantitative dynamic cellular imaging based on 3D unwrapped optically computed phase microscopy. Applied Optics, 2022.
- Optically computed phase microscopy to assess cellular uptake of lipid nanoparticles. CLEO: Applications and Technology, 2022.
- A BODIPY-based far-red-absorbing fluorescent probe for hypochlorous acid imaging. ChemPhotoChem, 2022.
- Optically computed phase microscopy for quantitative dynamic imaging of label-free cells and nanoparticles. Biomedical Optics Express, 2021.
- Potassium Ion Fluorescence Probes: Structures, Properties, and Bioimaging. ChemPhotoChem, 2021.
- Regulating mitochondrial pH with light and implications for chemoresistance. Chemistry - A European Journal, 2021.
- Light-responsive compounds and photo-uncaging. Bulletin of the American Physical Society, 2020.
- BODIPY-Based Photoacid Generators for Light-Induced Cationic Polymerization. Organic Letters, 2020. Co-first author.
- Photo-Uncaging of BODIPY Oxime Ester for Histone Deacetylases Induced Apoptosis in Tumor Cells. Chemical Communications, 2019.
Meetings
Scientific Meetings
- American Physical Society Mid-Atlantic Section Annual Meeting, 2020.
- ACS Fall 2021, Division of Biochemical Technology.
- The 3rd International Conference on Photopharmacology, 2021.
Contact
Contact
For research collaboration, industry opportunities, or scientific discussion, please reach out by email.